IDR-1

Modify Date: 2024-01-30 11:51:54

IDR-1 Structure
IDR-1 structure
 Common Name IDR-1
CAS Number 940291-10-1 Molecular Weight 242.31500
Density N/A Boiling Point N/A
Molecular Formula C65H118N18O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IDR-1


IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release[1][2].

 Names

Name (2S)-1-formyl-N-[(2S)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide,propane
Synonym More Synonyms

 IDR-1 Biological Activity

Description IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release[1][2].
Related Catalog
References

[1]. Monisha G Scott, et al. An Anti-Infective Peptide That Selectively Modulates the Innate Immune Response. Nat Biotechnol. 2007 Apr;25(4):465-72.

[2]. Man Hou, et al. Antimicrobial Peptide LL-37 and IDR-1 Ameliorate MRSA Pneumonia in Vivo. Cell Physiol Biochem. 2013;32(3):614-23.

 Chemical & Physical Properties

Molecular Formula C65H118N18O15
Molecular Weight 242.31500
Exact Mass 242.16300
PSA 69.97000
LogP 2.14120
InChIKey RCTYDUUDOSRQTI-WSZWBAFRSA-N
SMILES CC(C=O)NC(=O)C1CCCN1C=O.CCC

 Synonyms

IDR-1
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Chemsrc provides IDR-1(CAS#:940291-10-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of IDR-1 are included as well.>> amp version: IDR-1

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