N-(DITHIOCARBAMOYL)-N-METHYL-D-GLUCAMINE, SODIUM SALT

Modify Date: 2024-01-03 14:03:23

N-(DITHIOCARBAMOYL)-N-METHYL-D-GLUCAMINE, SODIUM SALT Structure
N-(DITHIOCARBAMOYL)-N-METHYL-D-GLUCAMINE, SODIUM SALT structure
Common Name N-(DITHIOCARBAMOYL)-N-METHYL-D-GLUCAMINE, SODIUM SALT
CAS Number 94161-07-6 Molecular Weight 308.35100
Density 1.542g/cm3 Boiling Point 551.8ºC at 760 mmHg
Molecular Formula C8H17N2NaO5S2 Melting Point N/A
MSDS N/A Flash Point 287.5ºC

 Use of N-(DITHIOCARBAMOYL)-N-METHYL-D-GLUCAMINE, SODIUM SALT


N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound 109Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication[1].

 Names

Name methyl-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]carbamodithioic acid
Synonym More Synonyms

  Biological Activity

Description N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound 109Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication[1].
Related Catalog
In Vivo N-methyl-N-dithiocarboxyglucamine (684-2736 mg/kg;腹腔注射,每日注射 3 次) 3 天内有效促进粪便镉排泄[1]。 N-methyl-N-dithiocarboxyglucamine (2736 mg/kg;腹腔注射,每周注射 3 次) 降低肾脏和肝脏的镉水平[1]。 Animal Model: Mice with CdCl2 injection[1] Dosage: 684, 1368 and 2736 mg/kg Administration: Intraperitoneal injection; 684, 1368 and 2736 mg/kg, three daily injection Result: Dose-dependently increased fecal Cd excretion and caused a fecal Cd excretion of almost 30% of the administered Cd over a 3-day period at a dose of 2736 mg/kg.
References

[1]. Gale GR, et al. Effects of sodium N-methyl-N-dithiocarboxyglucamine on cadmium distribution and excretion. Life Sci. 1984 Dec 17;35(25):2571-8.  

 Chemical & Physical Properties

Density 1.542g/cm3
Boiling Point 551.8ºC at 760 mmHg
Molecular Formula C8H17N2NaO5S2
Molecular Weight 308.35100
Flash Point 287.5ºC
Exact Mass 308.04800
PSA 148.51000
Index of Refraction 1.667

 Synonyms

N-Methyl-D-glucamine dithiocarbamate