DPC AJ1951

Modify Date: 2025-09-12 06:27:40

DPC AJ1951 Structure
DPC AJ1951 structure
Common Name DPC AJ1951
CAS Number 943519-33-3 Molecular Weight 448.45
Density N/A Boiling Point N/A
Molecular Formula C17H29FN6O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DPC AJ1951


DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR) , and characterized its activity in ex vivo and in vivo assays of bone resorption[1].

 Names

Name DPC-AJ1951

 DPC AJ1951 Biological Activity

Description DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR) , and characterized its activity in ex vivo and in vivo assays of bone resorption[1].
Related Catalog
In Vitro DPC-AJ1951 induces intracellular Ca2+ mobilization in HEK 293 cells transfected with the human PPR (EC50 26±14 nM)[1][1].
References

[1]. Percy H Carter, et al. Discovery of a Small Molecule Antagonist of the Parathyroid Hormone Receptor by Using an N-terminal Parathyroid Hormone Peptide Probe. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6846-51.

 Chemical & Physical Properties

Molecular Formula C17H29FN6O7
Molecular Weight 448.45
InChIKey PNJXWIJKATVXEY-FAQCDESUSA-N
SMILES CCCCC(NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(CCC(=O)O)NC(=O)C(C)(C)NC(=O)C(NC(=O)C(C)(C)N)C(C)C)C(C)CC)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CCC(N)=O)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(Cc1ccc(O)cc1)C(N)=O
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