D-Tyrosine-d4

Modify Date: 2024-01-07 13:05:44

D-Tyrosine-d4 Structure
D-Tyrosine-d4 structure
Common Name D-Tyrosine-d4
CAS Number 944386-47-4 Molecular Weight 185.21
Density N/A Boiling Point N/A
Molecular Formula C9H7D4NO3 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of D-Tyrosine-d4


D-Tyrosine-d4 is the deuterium labeled D-Tyrosine. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth[1][2].

 Names

Name D-Tyrosine-2,3,5,6-d4

 D-Tyrosine-d4 Biological Activity

Description D-Tyrosine-d4 is the deuterium labeled D-Tyrosine. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Jisu Park, et al. D-tyrosine Negatively Regulates Melanin Synthesis by Competitively Inhibiting Tyrosinase Activity. Pigment Cell Melanoma Res. 2018 May;31(3):374-383.

[3]. Cong Yu, et al. Inhibition of Biofilm Formation by D-tyrosine: Effect of Bacterial Type and D-tyrosine Concentration. Water Res. 2016 Apr 1;92:173-9.

 Chemical & Physical Properties

Molecular Formula C9H7D4NO3
Molecular Weight 185.21
Exact Mass 181.07400
PSA 83.55000
LogP 1.04690