Tomaymycin DM

Modify Date: 2024-01-22 14:41:40

Tomaymycin DM Structure
Tomaymycin DM structure
Common Name Tomaymycin DM
CAS Number 945490-09-5 Molecular Weight 258.27
Density N/A Boiling Point N/A
Molecular Formula C14H14N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tomaymycin DM


Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).

 Names

Name Tomaymycin DM

 Tomaymycin DM Biological Activity

Description Tomaymycin DM, a DNA alkylator, is a derivative of Tomaymycin, it is a PBD dimer, which is attached to tumor targeting antibodies to create antibody-drug conjugates (ADCs).
Related Catalog
Target

Pyrrolobenzodiazepines

References

[1]. Dr. Julia Mantaj, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody–Drug Conjugates (ADCs). Angew Chem Int Ed Engl. 2017 Jan 9; 56(2): 462–488.

 Chemical & Physical Properties

Molecular Formula C14H14N2O3
Molecular Weight 258.27