3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile
Modify Date: 2024-09-12 22:26:33
![3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile Structure](https://www.chemsrc.com/caspic/390/946400-19-7.png)
3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile structure
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Common Name | 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile | ||
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| CAS Number | 946400-19-7 | Molecular Weight | 461.86 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H16ClF4N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM. |
| Name | 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile |
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| Description | 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM. |
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| References | 1. Wan ZK, et al. Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J Med Chem. 2009 Sep 10;52(17):5449-61. |
| Molecular Formula | C19H16ClF4N3O2S |
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| Molecular Weight | 461.86 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 3-chloro-4-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-Benzonitrile
- Price: Negotiable
- Purity: 99.46%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
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