MNI 137

Modify Date: 2024-04-09 11:58:33

MNI 137 structure	Common Name	MNI 137
	CAS Number	946619-21-2	Molecular Weight	341.16200
	Density	1.62±0.1 g/cm3 (20 °C, 760 mmHg)	Boiling Point	561.2±50.0 °C (760 mmHg)
	Molecular Formula	C₁₅H₉BrN₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MNI 137

MNI137 is a potent and selective negative allosteric modulator for group II mGluRs. MNI137 has IC50s values of 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization[1].

Name	2-Pyridinecarbonitrile, 4-(8-bromo-2,3-dihydro-2-oxo-1H-1,5-benzodiazepin-4-yl)
Synonym	More Synonyms

Description	MNI137 is a potent and selective negative allosteric modulator for group II mGluRs. MNI137 has IC50s values of 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
References	[1]. Hemstapat K, et al. A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors. J Pharmacol Exp Ther. 2007;322(1):254-264.

Density	1.62±0.1 g/cm3 (20 °C, 760 mmHg)
Boiling Point	561.2±50.0 °C (760 mmHg)
Molecular Formula	C₁₅H₉BrN₄O
Molecular Weight	341.16200
Exact Mass	339.99600
PSA	78.14000
LogP	2.75238

MNI 137

VU 0360172 hydrochloride

DC Chemicals Limited
China
Product Name: MNI137
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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MNI 137

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