112170-24-8
112170-24-8 structure
- Name: BCI-137
- Chemical Name: N-[(2,3-Dioxo-1,2,3,4-tetrahydro-6-quinoxalinyl)sulfonyl]alanine
- CAS Number: 112170-24-8
- Molecular Formula: C11H11N3O6S
- Molecular Weight: 313.286
- Catalog: Research Areas Infection
- Create Date: 2020-01-11 19:42:27
- Modify Date: 2024-02-19 21:51:50
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BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM; displaces Ago2 from the miR-155 host gene promoter paralleling an increase in histone H4 acetylation, favors RA-induced differentiation of the APL cell line NB4.
| Name | N-[(2,3-Dioxo-1,2,3,4-tetrahydro-6-quinoxalinyl)sulfonyl]alanine |
|---|---|
| Synonyms |
N-[(2,3-Dioxo-1,2,3,4-tetrahydro-6-quinoxalinyl)sulfonyl]alanine
Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]- MFCD05148320 |
| Description | BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM; displaces Ago2 from the miR-155 host gene promoter paralleling an increase in histone H4 acetylation, favors RA-induced differentiation of the APL cell line NB4. |
|---|---|
| References | References 1. Masciarelli S, et al. ACS Chem Biol. 2014 Aug 15;9(8):1674-9. View Related Products by Target Other Targets |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C11H11N3O6S |
| Molecular Weight | 313.286 |
| Exact Mass | 313.036865 |
| LogP | -1.30 |
| Index of Refraction | 1.612 |