glycycoumarin

Modify Date: 2024-01-06 09:31:20

glycycoumarin Structure
glycycoumarin structure
 Common Name glycycoumarin
CAS Number 94805-82-0 Molecular Weight 368.380
Density 1.3±0.1 g/cm3 Boiling Point 646.9±55.0 °C at 760 mmHg
Molecular Formula C21H20O6 Melting Point 243.5-244.5℃
MSDS N/A Flash Point 232.0±25.0 °C

 Use of glycycoumarin


Glycycoumarin is a major bioactive coumarin of licorice. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase [1] [2].

 Names

Name glycycoumarin
Synonym More Synonyms

 glycycoumarin Biological Activity

Description Glycycoumarin is a major bioactive coumarin of licorice. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase [1] [2].
Related Catalog
References

[1]. Zhang E, et al. Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. Sci Rep. 2016 Nov 30;6:38138.

[2]. Song X, et al. Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase. Oncotarget. 2016 Oct 4;7(40):65732-65743.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 646.9±55.0 °C at 760 mmHg
Melting Point 243.5-244.5℃
Molecular Formula C21H20O6
Molecular Weight 368.380
Flash Point 232.0±25.0 °C
Exact Mass 368.125977
PSA 100.13000
LogP 5.99
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.649

 Safety Information

Hazard Codes Xi

 Synonyms

3-(2,4-Dihydroxy-phenyl)-7-hydroxy-5-methoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-2-one
3-(2,4-Dihydroxyphenyl)-7-hydroxy-5-methoxy-6-(3-methyl-2-buten-1-yl)-2H-chromen-2-one
glycycoumarin
2H-1-Benzopyran-2-one, 3-(2,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-6-(3-methyl-2-buten-1-yl)-
3-(2,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)chromen-2-one
Top Suppliers:I want be here

Get all suppliers and price by the below link:

glycycoumarin suppliers

glycycoumarin price

Related Compounds: More...
Glycycoumarin trimethylether
66056-33-5
Chemsrc provides glycycoumarin(CAS#:94805-82-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of glycycoumarin are included as well.>> amp version: glycycoumarin

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved