2,4-Dichlorotoluene

Modify Date: 2024-01-02 02:20:41

2,4-Dichlorotoluene Structure
2,4-Dichlorotoluene structure
Common Name 2,4-Dichlorotoluene
CAS Number 95-73-8 Molecular Weight 161.029
Density 1.2±0.1 g/cm3 Boiling Point 198.6±20.0 °C at 760 mmHg
Molecular Formula C7H6Cl2 Melting Point -14 °C
MSDS Chinese USA Flash Point 79.4±0.0 °C

 Names

Name 2,4-Dichlorotoluene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 198.6±20.0 °C at 760 mmHg
Melting Point -14 °C
Molecular Formula C7H6Cl2
Molecular Weight 161.029
Flash Point 79.4±0.0 °C
Exact Mass 159.984650
LogP 3.88
Vapour Pressure 0.5±0.4 mmHg at 25°C
Index of Refraction 1.543
Water Solubility immiscible

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT0730000
CHEMICAL NAME :
Toluene, 2,4-dichloro-
CAS REGISTRY NUMBER :
95-73-8
BEILSTEIN REFERENCE NO. :
1931691
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C7-H6-Cl2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - muscle weakness
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(10),56,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - muscle weakness
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(10),56,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 53(2),80,1988 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6440 mg/kg/2W-I
TOXIC EFFECTS :
Liver - other changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 52(11),86,1987
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
28980 mg/kg/9W-I
TOXIC EFFECTS :
Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 53(2),80,1988

 Safety Information

Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S23-S24/25
RIDADR UN 2810
WGK Germany 2
RTECS XT0730000
Packaging Group III
Hazard Class 9
HS Code 29036990

 Synthetic Route

 Customs

HS Code 2903999090
Summary 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles7

More Articles
Metabolism of dichloromethylcatechols as central intermediates in the degradation of dichlorotoluenes by Ralstonia sp. strain PS12.

J. Bacteriol. 184(19) , 5261-74, (2002)

Ralstonia sp. strain PS12 is able to use 2,4-, 2,5-, and 3,4-dichlorotoluene as growth substrates. Dichloromethylcatechols are central intermediates that are formed by TecA tetrachlorobenzene dioxygen...

Development of a solid-phase microextraction-gas chromatography-tandem mass spectrometry method for the analysis of chlorinated toluenes in environmental waters.

J. Chromatogr. A. 1216(14) , 2816-24, (2009)

In the present work, a simple and fast methodology has been developed for the analysis of chlorotoluenes in water samples using solid-phase microextraction (SPME) coupled to gas chromatography-tandem ...

Rapid and selective catalytic oxidation of secondary alcohols at room temperature by using (N-heterocyclic carbene)-ni(0) systems.

Chemistry 16(23) , 6857-60, (2010)

The selective, anaerobic catalytic oxidation of secondary alcohols at room temperature by using an in situ (N-heterocyclic carbene)-Ni(0) system is presented. The use of non-anhydrous, non-degassed 2,...

 Synonyms

2,4-Dichlorotoluene
2,4-Dichlor-toluol
2,4-dichloro-1-methyl-benzene
2,4-Dichloro-1-methylbenzene
EINECS 202-445-8
2,4-dichloro-toluene
Benzene, 2,4-dichloro-1-methyl-
4,6-dichlorothieno<2,3-b>pyridine
MFCD00000583
4,6-dichlorotoluene
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