Phytochelatin 2 (PC2)

Modify Date: 2024-01-03 10:41:35

Phytochelatin 2 (PC2) structure	Common Name	Phytochelatin 2 (PC2)
	CAS Number	95014-75-8	Molecular Weight	539.58000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₉N₅O₁₀S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Phytochelatin 2 (PC2)

Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis[1][2].

Name	H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin B (2))
Synonym	More Synonyms

Description	Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Phytochelatin synthase (PCS) uses the substrates glutathione (GSH, γGlu-Cys-Gly) and a cadmium (Cd)-bound GSH (Cd∙GS2) to produce the shortest phytochelatin product (PC2, (γGlu-Cys)2-Gly) through a ping-pong mechanism[3]. Phytochelatins and their glutathione (GSH) precursor are thiol-rich peptides that play an important role in heavy metal detoxification in plants and microorganisms[4].
References	[1]. phytochelatin, heavy, metals, chelate, homeostasis, glutathione, microorganisms, toxicity [2]. Dennis KK, et al. Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental metals. Database (Oxford). 2019;2019:baz083. [3]. Chia JC, et al. Tentative identification of the second substrate binding site in Arabidopsis phytochelatin synthase. PLoS One. 2013;8(12):e82675. Published 2013 Dec 5. [4]. Jacquart A, et al. Cd2+ and Pb2+ complexation by glutathione and the phytochelatins. Chem Biol Interact. 2017;267:2-10.