TTP-8307
Modify Date: 2025-09-18 11:52:37
TTP-8307 structure
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Common Name | TTP-8307 | ||
|---|---|---|---|---|
| CAS Number | 950225-08-8 | Molecular Weight | 436.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H21FN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TTP-8307TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307. |
| Name | TTP-8307 |
|---|
| Description | TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307. |
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| References | References 1. De Palma AM, et al. Antimicrob Agents Chemother. 2009 May;53(5):1850-7. 2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72. 3. Norder H, et al. Antiviral Res. 2011 Mar;89(3):204-18. View Related Products by Target Enterovirus |
| Molecular Formula | C27H21FN4O |
|---|---|
| Molecular Weight | 436.49 |
| InChIKey | SIBDJDZVNXVLEX-QGZVFWFLSA-N |
| SMILES | CC(NC(=O)c1cccc(-c2cnc(-c3cc4ccccc4cn3)[nH]2)c1)c1ccc(F)cc1 |