TTP-8307

Modify Date: 2024-06-21 02:32:39

TTP-8307 Structure
TTP-8307 structure
Common Name TTP-8307
CAS Number 950225-08-8 Molecular Weight 436.49
Density N/A Boiling Point N/A
Molecular Formula C27H21FN4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TTP-8307


TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307.

 Names

Name TTP-8307

 TTP-8307 Biological Activity

Description TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307.
References References 1. De Palma AM, et al. Antimicrob Agents Chemother. 2009 May;53(5):1850-7. 2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72. 3. Norder H, et al. Antiviral Res. 2011 Mar;89(3):204-18. View Related Products by Target Enterovirus

 Chemical & Physical Properties

Molecular Formula C27H21FN4O
Molecular Weight 436.49
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