329907-28-0
329907-28-0 structure
- Name: TTP 22
- Chemical Name: 3-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylpropanoic acid
- CAS Number: 329907-28-0
- Molecular Formula: C16H14N2O2S2
- Molecular Weight: 330.425
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Casein Kinase
- Create Date: 2017-05-14 01:13:35
- Modify Date: 2024-01-09 19:01:34
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TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM.
| Name | 3-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylpropanoic acid |
|---|---|
| Synonyms |
3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid
TTP-22 Propanoic acid, 3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]- HMS1423O22 3-{[5-(4-Methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanyl}propanoic acid TTP22 TTP 22 |
| Description | TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. |
|---|---|
| Related Catalog | |
| Target |
CK2:100 nM (IC50) |
| In Vitro | TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 575.0±50.0 °C at 760 mmHg |
| Molecular Formula | C16H14N2O2S2 |
| Molecular Weight | 330.425 |
| Flash Point | 301.6±30.1 °C |
| Exact Mass | 330.049683 |
| PSA | 116.62000 |
| LogP | 4.21 |
| Appearance | white solid |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.710 |
| Storage condition | -20℃ |
| Precursor 2 | |
|---|---|
| DownStream 0 | |