Erianin

Modify Date: 2024-01-02 09:58:28

Erianin Structure
Erianin structure
Common Name Erianin
CAS Number 95041-90-0 Molecular Weight 318.364
Density 1.1±0.1 g/cm3 Boiling Point 439.1±40.0 °C at 760 mmHg
Molecular Formula C18H22O5 Melting Point N/A
MSDS N/A Flash Point 219.4±27.3 °C

 Use of Erianin


Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

 Names

Name 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol
Synonym More Synonyms

 Erianin Biological Activity

Description Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.
Related Catalog
In Vitro Erianin is often used as antipyretic and analgesic agent. Erianin belongs to bibenzyl derivatives in structure, with the activity of anti-virus, anti-bacterial, as well as anti-benign prostatic hyperplasia. Erianin has obvious damage on 2LL-IDO cells, Erianin basically has no cytotoxicity on human normal liver cell line L02, and cell viability is maintained at around 85%[1]. Erianin inhibits the growth of HeLa cells and induces apoptosis in a dose‑ and time‑dependent manner, inducing cell cycle arrest at the G2/M stage. Erianin treatment also increases the expression of Bax and caspase‑3, but decreases levels of Bcl‑2 and phosphorylated‑ERK1/2[2].
References

[1]. Su C, et al. Erianin inhibits indoleamine 2, 3-dioxygenase -induced tumor angiogenesis. Biomed Pharmacother. 2017 Apr;88:521-528.

[2]. Li M, et al. Erianin inhibits human cervical cancer cell through regulation of tumor protein p53 via the extracellular signal-regulated kinase signaling pathway. Oncol Lett. 2018 Oct;16(4):5006-5012.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 439.1±40.0 °C at 760 mmHg
Molecular Formula C18H22O5
Molecular Weight 318.364
Flash Point 219.4±27.3 °C
Exact Mass 318.146729
PSA 57.15000
LogP 3.11
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.554

 Synthetic Route

 Synonyms

Phenol, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]-
Dihydrocombretatastin A-4
Erianin
2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)-ethyl]-phenol
5-(3,4,5-trimethoxyphenethyl)-2-methoxyphenol
2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol
(E)-2-methoxy-5-(3,4,5-trimethoxyphenylethyl)phenol
3-hydroxy-3',4',4,5'-tetramethoxybibenzyl
2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]benzolol
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Price: ¥660/10 mM * 1 mL in DMSO

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