GKT136901

Modify Date: 2024-02-02 13:35:48

GKT136901 Structure
GKT136901 structure
Common Name GKT136901
CAS Number 955272-06-7 Molecular Weight 366.80100
Density N/A Boiling Point N/A
Molecular Formula C19H15ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GKT136901


GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 also is a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity.

 Names

Name 2-(2-Chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C19H15ClN4O2
Molecular Weight 366.80100
Exact Mass 366.08800
PSA 72.68000
LogP 2.88560
InChIKey DNKYHHFCPXKFIY-UHFFFAOYSA-N
SMILES Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccccn1

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,3-c]pyridine-3,6-dione
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