AGN 196996
Modify Date: 2024-01-05 17:07:19
AGN 196996 structure
|
Common Name | AGN 196996 | ||
|---|---|---|---|---|
| CAS Number | 958295-17-5 | Molecular Weight | 482.32300 | |
| Density | 1.453±0.06 g/cm3 (20 °C, 760 mmHg) | Boiling Point | 619.8±55.0 °C (760 mmHg) | |
| Molecular Formula | C24H20BrNO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AGN 196996AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).IC50 value: 2 nM(Ki)Target: RARα antagonistAGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. |
| Name | Benzoic acid, 4-[[3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino] |
|---|---|
| Synonym | More Synonyms |
| Description | AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).IC50 value: 2 nM(Ki)Target: RARα antagonistAGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.453±0.06 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Boiling Point | 619.8±55.0 °C (760 mmHg) |
| Molecular Formula | C24H20BrNO5 |
| Molecular Weight | 482.32300 |
| Exact Mass | 481.05200 |
| PSA | 92.70000 |
| LogP | 5.41070 |
| Storage condition | 2-8℃ |
| AGN 196996 |