Daprodustat
Modify Date: 2024-01-02 16:48:38
Daprodustat structure
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Common Name | Daprodustat | ||
|---|---|---|---|---|
| CAS Number | 960539-70-2 | Molecular Weight | 393.434 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C19H27N3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DaprodustatDaprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor being developed for the treatment of anemia associated with chronic kidney disease. |
| Name | Daprodustat |
|---|---|
| Synonym | More Synonyms |
| Description | Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor being developed for the treatment of anemia associated with chronic kidney disease. |
|---|---|
| Related Catalog | |
| In Vitro | GSK1278863 is an orally administered small-molecule PHI, and stimulates endogenous EPO synthesis and induce effective erythropoiesis[1]. GSK1278863 has been shown to increase erythropoietin levels, leading to increases in hemoglobin, hematocrit and red blood cell numbers[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C19H27N3O6 |
| Molecular Weight | 393.434 |
| Exact Mass | 393.189972 |
| PSA | 124.09000 |
| LogP | 0.86 |
| Appearance of Characters | white solid |
| Index of Refraction | 1.580 |
| Storage condition | -20℃ |
| N-[(1,3-Dicyclohexyl-2,4,6-trioxohexahydro-5-pyrimidinyl)carbonyl]glycine |
| (1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine |
| GSK-1278863 |
| Glycine, N-[(1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl]- |
| UNII:JVR38ZM64B |
| daprodustat |
| 2-(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carboxamido)acetic acid |
| GSK1278863 |