Crisnatol mesylate
Modify Date: 2024-01-05 12:35:02
Crisnatol mesylate structure
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Common Name | Crisnatol mesylate | ||
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| CAS Number | 96389-69-4 | Molecular Weight | 441.54000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H27NO5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Crisnatol mesylateCrisnatol (BWA770U) mesylate is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol mesylate shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts[1][2][3]. |
| Name | 2-(chrysen-6-ylmethylamino)-2-methylpropane-1,3-diol,methanesulfonic acid |
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| Synonym | More Synonyms |
| Description | Crisnatol (BWA770U) mesylate is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol mesylate shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts[1][2][3]. |
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| Related Catalog | |
| In Vitro | Crisnatol (1.3 μg/mL; 24-72 h) mesylate 抑制 HepG2 细胞的复制，使细胞活力降低 35%[2]。 Cell Viability Assay[2] Cell Line: HepG2 cells Concentration: 1.3 μg/mL Incubation Time: 24 hours, 48 hours, 72 hours, and 126 hours Result: Inhibited cell viability at 48 hr. |
| In Vivo | Crisnatol (25 mg/kg; p.o.; single dose) mesylate 显示出口服活性，并通过放射自显影显示大鼠粪便提取物的稳定代谢物谱[2]。 |
| References |
| Molecular Formula | C24H27NO5S |
|---|---|
| Molecular Weight | 441.54000 |
| Exact Mass | 441.16100 |
| PSA | 115.24000 |
| LogP | 4.95480 |
| Crisnatol mesilate |
| CRISNATOL MESYLATE |
| BW-A770U mesylate |
| 770U82 Mesylate |