Nyasol

Modify Date: 2026-07-21 13:40:44

Nyasol structure	Common Name	Nyasol
	CAS Number	96895-25-9	Molecular Weight	252.31
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Nyasol

Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells[1][2].

Name	4-[(1E,3R)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol
Synonym	More Synonyms

Description	Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Lim H, et al. (-)-Nyasol (cis-hinokiresinol), a norneolignan from the rhizomes of Anemarrhena asphodeloides, is a broad spectrum inhibitor of eicosanoid and nitric oxide production. Arch Pharm Res. 2009 Nov;32(11):1509-14. [2]. Iida Y, et al. In vitro synergism between nyasol, an active compound isolated from Anemarrhena asphodeloides, and azole agents against Candida albicans. Planta Med. 2000 Jun;66(5):435-8. [3]. Lee HJ, et al. (-)-Nyasol, isolated from Anemarrhena asphodeloides suppresses neuroinflammatory response through the inhibition of I-κBα degradation in LPS-stimulated BV-2 microglial cells. J Enzyme Inhib Med Chem. 2013 Oct;28(5):954-9.

Description

Related Catalog

Research Areas >> Infection

Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Lim H, et al. (-)-Nyasol (cis-hinokiresinol), a norneolignan from the rhizomes of Anemarrhena asphodeloides, is a broad spectrum inhibitor of eicosanoid and nitric oxide production. Arch Pharm Res. 2009 Nov;32(11):1509-14.

[2]. Iida Y, et al. In vitro synergism between nyasol, an active compound isolated from Anemarrhena asphodeloides, and azole agents against Candida albicans. Planta Med. 2000 Jun;66(5):435-8.

[3]. Lee HJ, et al. (-)-Nyasol, isolated from Anemarrhena asphodeloides suppresses neuroinflammatory response through the inhibition of I-κBα degradation in LPS-stimulated BV-2 microglial cells. J Enzyme Inhib Med Chem. 2013 Oct;28(5):954-9.

Molecular Formula	C₁₇H₁₆O₂
Molecular Weight	252.31
Exact Mass	252.11500
PSA	40.46000
LogP	4.08080
InChIKey	VEAUNWQYYMXIRB-JHAQOBCDSA-N
SMILES	C=CC(C=Cc1ccc(O)cc1)c1ccc(O)cc1

Name: Cytotoxicity against human Lu1 cells
Source: ChEMBL
Target: Lu1
External Id: CHEMBL1036067

Name: Selectivity index, ratio of IC50 for human lymphocyte to IC50 for chloroquine-resista...
Source: ChEMBL
Target: N/A
External Id: CHEMBL958539

Name: Cytotoxicity against HUVEC
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL1036068

Name: Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (...
Source: NCGC
External Id: IP6K1-p1

Name: Cytotoxicity against human Col2 cells
Source: ChEMBL
Target: Col2
External Id: CHEMBL1036065

Name: Cytotoxicity against human LNCAP cells
Source: ChEMBL
Target: LNCaP
External Id: CHEMBL1036066

Name: Cytotoxicity against human HOG.R5 cells
Source: ChEMBL
Target: N/A
External Id: CHEMBL1036063

Name: Selectivity index, ratio of IC50 for human lymphocyte to IC50 for Leishmania major
Source: ChEMBL
Target: N/A
External Id: CHEMBL958535

Name: Cytotoxicity against human KB cells
Source: ChEMBL
Target: KB
External Id: CHEMBL1036064

Name: Selectivity index, ratio of IC50 for human lymphocyte to IC50 for chloroquine-suscept...
Source: ChEMBL
Target: N/A
External Id: CHEMBL958538

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4,4'-(3-Ethenyl-1-propene-1,3-diyl)-bisphenol

(+)-hinokiresinol

Nyasol

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Nyasol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

BioBioPha
China
Product Name: Nyasol
Price: ￥3750.0/5mg
Purity: 98.0%
Delivery: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

naturewill
China
Product Name: Nyasol
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.