cyproheptadine hydrochloride structure
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Common Name | cyproheptadine hydrochloride | ||
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CAS Number | 969-33-5 | Molecular Weight | 323.859 | |
Density | N/A | Boiling Point | 440.1ºC at 760mmHg | |
Molecular Formula | C21H22ClN | Melting Point | N/A | |
MSDS | Chinese | Flash Point | 194.5ºC |
Use of cyproheptadine hydrochlorideCyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM. Target: 5-HT2 ReceptorCyproheptadine is a serotonin antagonist and a histamine H2 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc. Inhibitory effects of cyclobenzaprine, amitriptyline, and cyproheptadine on mono- and polysynaptic reflex potentials are due to the inhibition of descending serotonergic systems through 5-HT(2) receptors in the spinal cord [1, 2]. |
Name | cyproheptadine hydrochloride (anhydrous) |
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Synonym | More Synonyms |
Description | Cyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM. Target: 5-HT2 ReceptorCyproheptadine is a serotonin antagonist and a histamine H2 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc. Inhibitory effects of cyclobenzaprine, amitriptyline, and cyproheptadine on mono- and polysynaptic reflex potentials are due to the inhibition of descending serotonergic systems through 5-HT(2) receptors in the spinal cord [1, 2]. |
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Related Catalog | |
References |
[2]. Calka, O., et al., Effect of cyproheptadine on serum leptin levels. Adv Ther, 2005. 22(5): p. 424-8. |
Boiling Point | 440.1ºC at 760mmHg |
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Molecular Formula | C21H22ClN |
Molecular Weight | 323.859 |
Flash Point | 194.5ºC |
Exact Mass | 323.144073 |
PSA | 3.24000 |
LogP | 5.43780 |
Storage condition | Store at RT |
Water Solubility | ethanol: soluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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Hazard Codes | Xn: Harmful; |
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Risk Phrases | R22;R36/37/38 |
Safety Phrases | 26-36 |
RIDADR | UN 2811 |
WGK Germany | 3 |
RTECS | TM7050000 |
Packaging Group | III |
Hazard Class | 6.1(b) |
HS Code | 2933399090 |
HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride |
Piperidine, 4- (5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride |
periactinolhydrochloride |
cyproheptadienehydrochloride |
4-(5H-Dibenzo[a,d][7]annulen-5-yliden)-1-methylpiperidinhydrochlorid |
4-(5H-dibenzo[a,d][7]annulén-5-ylidène)-1-méthylpipéridine chlorhydrate |
piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride |
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine Hydrochloride |
CYPROHEPTADINE HCL BP |
peritol |
ANAREXOL |
Cyproheptadin |
Piperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (1:1) |
periactinhydrochloride |
MFCD00012538 |
cyproheptadine hydrochloride |
CYPROHEPTADINE HCL |
EINECS 213-535-1 |
Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (1:1) |
periactinsyrup |
4-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride (1:1) |
nuran |
1-Methyl-4-(5-dibenzo[a,e]cycloheptatrienylidene)piperidine hydrochloride |
1-Methyl-4-(5H-dibenzo[a,e]cycloheptatrienylidene)piperidine Hydrochloride |
Cyproheptadine (hydrochloride) |