α-Hydroxytamoxifen

Modify Date: 2025-08-25 13:02:49

α-Hydroxytamoxifen structure	Common Name	α-Hydroxytamoxifen
	CAS Number	97151-02-5	Molecular Weight	387.51400
	Density	1.094g/cm3	Boiling Point	533.8ºC at 760 mmHg
	Molecular Formula	C₂₆H₂₉NO₂	Melting Point	115-119ºC
	MSDS	N/A	Flash Point	276.6ºC

Use of α-Hydroxytamoxifen

α-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts[1].

Name	(E)-4-[4-[2-(dimethylamino)ethoxy]phenyl]-3,4-diphenylbut-3-en-2-ol
Synonym	More Synonyms

Description	α-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Phillips DH, et al. alpha-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes. Cancer Res. 1994 Nov 1;54(21):5518-22.

Density	1.094g/cm3
Boiling Point	533.8ºC at 760 mmHg
Melting Point	115-119ºC
Molecular Formula	C₂₆H₂₉NO₂
Molecular Weight	387.51400
Flash Point	276.6ºC
Exact Mass	387.22000
PSA	32.70000
LogP	5.70170
Index of Refraction	1.595
InChIKey	BPHFBQJMFWCHGH-QPLCGJKRSA-N
SMILES	CC(O)C(=C(c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1

HS Code	2922509090

ethyl 2-nitro-3...

CAS#:61923-53-3

α-Hydroxytamoxifen

CAS#:97151-02-5

Literature: Journal of Medicinal Chemistry, , vol. 28, # 10 p. 1491 - 1497

(E,Z)-1-Bromo-2...

CAS#:19118-19-5

2-[4-(1,2-diphe...

CAS#:19957-51-8

α-Hydroxytamoxifen

CAS#:97151-02-5

cis-a-Hydroxy T...

CAS#:97170-41-7

Literature: Journal of Medicinal Chemistry, , vol. 28, # 10 p. 1491 - 1497

(E,Z)-1-Bromo-2...

CAS#:19118-19-5

ch3cho

CAS#:75-07-0

2-[4-(1,2-diphe...

CAS#:19957-51-8

α-Hydroxytamoxifen

CAS#:97151-02-5

Detail

Literature: Journal of Medicinal Chemistry, , vol. 28, # 10 p. 1491 - 1497

Precursor 3
CAS#:61923-53-3 ethyl 2-nitro-3... CAS#:19118-19-5 (E,Z)-1-Bromo-2... CAS#:75-07-0 ch3cho
DownStream 0

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

trans-(E)-4-[4-(2-dimethylamino-ethoxy)-phenyl]-3,4-diphenyl-but-3-en-2-ol

(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-buten-3-ol

Trans-Hydroxy-Tamoxifen

(E)-|A-Hydroxy Tamoxifen

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α-Hydroxytamoxifen

Use of α-Hydroxytamoxifen

Names

α-Hydroxytamoxifen Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.