Pericyclivine

Modify Date: 2024-01-02 14:35:34

Pericyclivine structure	Common Name	Pericyclivine
	CAS Number	975-77-9	Molecular Weight	322.401
	Density	1.3±0.1 g/cm3	Boiling Point	489.2±45.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₂N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	249.7±28.7 °C

Use of Pericyclivine

Pericyclivine is a monomeric indole alkaloid isolated from Catharanthus Roseus. Pericyclivine has anticancer effects[1][2].

Name	(+)-Pericyclivine
Synonym	More Synonyms

Description	Pericyclivine is a monomeric indole alkaloid isolated from Catharanthus Roseus. Pericyclivine has anticancer effects[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Pericyclivine shows cytotoxicity against the P-388 cell culture system with an ED50 of 13 μg/mL[2].
References	[1]. S Mukhopadhyay, et al. Catharanthus Alkaloids. XXXVI. Isolation of Vincaleukoblastine (VLB) and Periformyline From Catharanthus Trichophyllus and Pericyclivine From Catharanthus Roseus. J Nat Prod. May-Jun 1981;44(3):335-9. [2]. D G Kingston, et al. Plant Anticancer Agents V: New Bisindole Alkaloids From Tabernaemontana Johnstonii Stem Bark. J Pharm Sci. 1978 Feb;67(2):249-51.

Density	1.3±0.1 g/cm3
Boiling Point	489.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂N₂O₂
Molecular Weight	322.401
Flash Point	249.7±28.7 °C
Exact Mass	322.168121
PSA	45.33000
LogP	3.50
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.673

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VQ5835000

CHEMICAL NAME :: Sarpagan-17-oic acid, methyl ester, (16S)-

CAS REGISTRY NUMBER :: 975-77-9

LAST UPDATED :: 197905

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H20-N2-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04199

Hazard Codes	Xi

pericyclivine

Pericyclivin

Desformoakuammidin

Sarpagan-17-oic acid, methyl ester, (15α)-

Methyl (15α,19E)-sarpagan-17-oate

sarpagan-17-oic acid methyl ester

Deformoakuammidine

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China
Product Name: Pericyclivine
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Purity: 98.0%
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BioBioPha
China
Product Name: Pericyclivine
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China
Product Name: 6,10-Methanoindolo[3,2-b]quinolizine-11-carboxylicacid, 9-ethylidene-5,6,8,9,10,11,11a,12-octahydro-, methyl ester,(6S,7R,9E,10R,11S,11aS)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
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