3-Aminobenzenesulfonamide

Modify Date: 2026-07-09 10:20:08

3-Aminobenzenesulfonamide Structure
3-Aminobenzenesulfonamide structure
Common Name 3-Aminobenzenesulfonamide
CAS Number 98-18-0 Molecular Weight 172.205
Density 1.4±0.1 g/cm3 Boiling Point 420.7±47.0 °C at 760 mmHg
Molecular Formula C6H8N2O2S Melting Point 139 °C
MSDS Chinese USA Flash Point 208.3±29.3 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 3-Aminobenzenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.4±0.1 g/cm3
Boiling Point 420.7±47.0 °C at 760 mmHg
Melting Point 139 °C
Molecular Formula C6H8N2O2S
Molecular Weight 172.205
Flash Point 208.3±29.3 °C
Exact Mass 172.030655
PSA 94.56000
LogP -1.20
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.628
InChIKey JPVKCHIPRSQDKL-UHFFFAOYSA-N
SMILES Nc1cccc(S(N)(=O)=O)c1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Name: 3-Aminobenzene-1-sulfonamide 97% Material Safety Data Sheet
Synonym:
CAS: 98-18-0
Section 1 - Chemical Product MSDS Name:3-Aminobenzene-1-sulfonamide 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
98-18-0 3-Aminobenzene-1-sulfonamide 97% 202-646-0
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 98-18-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 140 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H8N2O2S
Molecular Weight: 172

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials, exposure to air.
Incompatibilities with Other Materials:
Acids, oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide, ammonia.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 98-18-0: OY2200000 LD50/LC50:
Not available.
Carcinogenicity:
3-Aminobenzene-1-sulfonamide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 98-18-0: 1
Canada
CAS# 98-18-0 is listed on Canada's NDSL List.
CAS# 98-18-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 98-18-0 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OY2200000
CHEMICAL NAME :
Metanilamide
CAS REGISTRY NUMBER :
98-18-0
BEILSTEIN REFERENCE NO. :
0511851
LAST UPDATED :
199709
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H8-N2-O2-S
MOLECULAR WEIGHT :
172.22
WISWESSER LINE NOTATION :
ZSWR CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 10,319,1937 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81890 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 308 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
RTECS OY2200000
HS Code 2935009090

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Articles1

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Different land use intensities in grassland ecosystems drive ecology of microbial communities involved in nitrogen turnover in soil.

PLoS ONE 8 , e73536, (2013)

Understanding factors driving the ecology of N cycling microbial communities is of central importance for sustainable land use. In this study we report changes of abundance of denitrifiers, nitrifiers...

 3-AminobenzenesulfonamideBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Inhibitory activity against bovine carbonic anhydrase IV (bCAIV)
Source: ChEMBL
Target: Carbonic anhydrase 4
External Id: CHEMBL838574
Name: Inhibition of Vibrio cholerae alpha-carbonic anhydrase using CO2 as substrate preincu...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3761240
Name: Inhibition of Vibrio cholerae beta-carbonic anhydrase using CO2 as substrate preincub...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3760464
Name: Inhibitory constant against catalytic domain of human carbonic anhydrase XII
Source: ChEMBL
Target: Carbonic anhydrase 12
External Id: CHEMBL827186
Name: Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mi...
Source: ChEMBL
Target: Carbonic anhydrase 1
External Id: CHEMBL3761242
Name: Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mi...
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL3761241
Name: Inhibitory activity against Human carbonic anhydrase II
Source: ChEMBL
Target: Carbonic anhydrase 2
External Id: CHEMBL658042
Name: Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assay
Source: ChEMBL
Target: Carbonic anhydrase 1
External Id: CHEMBL3270415
Name: Inhibition of recombinant Methanosarcina thermophila gamma-CA CAM by stopped flow CO2...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3102348
Name: Inhibition of Porphyromonas gingivalis gamma-carbonic anhydrase expressed in Escheric...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3102349
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

m-Aminobenzenesulphonamide
aniline-3-sulfonic acid amide
Metaniilamide
3-aminobenzene-1-sulfonamide
3-Aminobenzenesulphonamide
MFCD00035781
m-Sulfamoylaniline
3-Amino-benzenesulfonamide
EINECS 202-646-0
m-Aminobenzenesulfonamide
3-Aminobenzenesulfonamide
Metanilamide
3-AMINOBENZOL-1-SULFONAMID
Benzenesulfonamide,m-amino
m-Amino benzene sulfonanilide
Benzenesulfonamide,3-amino
3-AMINO BENZENESULFONAMIDE

 3-Aminobenzenesulfonamide | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the melting point of 3-Aminobenzenesulfonamide?
A: Melting point of 3-Aminobenzenesulfonamide is 139 °C.
Q: What is the English name of 3-Aminobenzenesulfonamide?
A: The English name of 3-Aminobenzenesulfonamide is 3-Aminobenzenesulfonamide.
Q: What is the safety information for 3-Aminobenzenesulfonamide?
A: Safety information for 3-Aminobenzenesulfonamide: S24/25.
Q: What is the CAS number of 3-Aminobenzenesulfonamide?
A: CAS number of 3-Aminobenzenesulfonamide is 98-18-0.
Q: What is the polar surface area (PSA) of 3-Aminobenzenesulfonamide?
A: Polar surface area (PSA) of 3-Aminobenzenesulfonamide is 94.56000.
Q: What is the LogP of 3-Aminobenzenesulfonamide?
A: LogP of 3-Aminobenzenesulfonamide is -1.20.
Q: What are the upstream materials of 3-Aminobenzenesulfonamide?
A: Related upstream materials(CAS) of 3-Aminobenzenesulfonamide: 121-52-8;121-51-7;127-68-4;3887-48-7.
Q: What is the boiling point of 3-Aminobenzenesulfonamide?
A: Boiling point of 3-Aminobenzenesulfonamide is 420.7±47.0 °C at 760 mmHg.
Q: What is the SMILES notation of 3-Aminobenzenesulfonamide?
A: SMILES notation of 3-Aminobenzenesulfonamide is Nc1cccc(S(N)(=O)=O)c1.
Q: What is the InChIKey of 3-Aminobenzenesulfonamide?
A: InChIKey of 3-Aminobenzenesulfonamide is JPVKCHIPRSQDKL-UHFFFAOYSA-N.

 3-Aminobenzenesulfonamidefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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