Pyrazine-2-carboxylic acid
Pyrazine-2-carboxylic acid structure
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Common Name | Pyrazine-2-carboxylic acid | ||
|---|---|---|---|---|
| CAS Number | 98-97-5 | Molecular Weight | 124.10 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 313.1±22.0 °C at 760 mmHg | |
| Molecular Formula | C5H4N2O2 | Melting Point | 222-225 °C (dec.)(lit.) | |
| MSDS | N/A | Flash Point | 143.1±22.3 °C | |
Use of Pyrazine-2-carboxylic acidPyrazine-2-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | pyrazine-2-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Pyrazine-2-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | |
| In Vitro | 吡嗪羧酸是吡嗪酰胺的活性代谢物。Pyrazinamidean 是一种抗结核剂。在这个用于评估促尿酸药物作用的模型中，丙磺舒减少了吡嗪羧酸的尿排泄，表明尿酸盐和吡嗪羧酸的尿排泄之间呈负相关。在体外研究中，用吡嗪羧酸处理大鼠肾刷状缘膜的囊泡会增加尿酸盐的摄取，而尿酸盐摄取会被排尿酸药物抑制。PZA（吡嗪酰胺）在植物细胞中转化为吡嗪羧酸 (POA)，抑制 1-氨基环丙烷-1-羧酸氧化酶 (ACO) 的活性，该酶催化乙烯形成的最后一步 。 |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 313.1±22.0 °C at 760 mmHg |
| Melting Point | 222-225 °C (dec.)(lit.) |
| Molecular Formula | C5H4N2O2 |
| Molecular Weight | 124.10 |
| Flash Point | 143.1±22.3 °C |
| Exact Mass | 124.027275 |
| PSA | 63.08000 |
| LogP | -1.36 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.579 |
| InChIKey | NIPZZXUFJPQHNH-UHFFFAOYSA-N |
| SMILES | O=C(O)c1cnccn1 |
| Water Solubility | SOLUBLE IN COLD WATER |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi,C,F |
|---|---|
| Risk Phrases | R11 |
| Safety Phrases | S22-S24/25 |
| WGK Germany | 3 |
| HS Code | 29339990 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 10 | |
CAS#:89-01-0
CAS#:109-08-0
CAS#:13925-00-3
CAS#:98-96-4
CAS#:13961-37-0
CAS#:13481-25-9
CAS#:6924-68-1
CAS#:123-32-0
CAS#:34569-20-5
CAS#:107-21-1
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CAS#:402958-98-9
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CAS#:23688-89-3This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Minimum Inhibitory Concentration against Mycobacterium tuberculosis ATCC 27294
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL750947
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: Minimum Inhibitory Concentration against Mycobacterium tuberculosis ATCC 35801
Source: ChEMBL
Target: Mycobacterium tuberculosis
External Id: CHEMBL750948
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Antimycobacterial activity against POA-resistant Mycobacterium bovis BCG harboring Pa...
Source: ChEMBL
Target: Mycobacterium tuberculosis variant bovis
External Id: CHEMBL5099099
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Name: Binding affinity to Mycobacterium tuberculosis PanD assessed as dissociation constant...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5099100
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Binding affinity to Mycobacterium tuberculosis PanD assessed as change in enthalpy by...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5099101
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Name: Binding affinity to Mycobacterium tuberculosis PanD assessed as change in entropy by ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5099102
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00006130 |
| 2-Pyrazinecarboxylic acid |
| Pyrazinoic acid |
| Pyrazine-2-carboxylic acid |
| EINECS 202-718-1 |
| Pyrazine Carboxylic Acid |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of pyrazine-2-carboxylic acid? |
| A: Polar surface area (PSA) of pyrazine-2-carboxylic acid is 63.08000. |
| Q: What is the boiling point of pyrazine-2-carboxylic acid? |
| A: Boiling point of pyrazine-2-carboxylic acid is 313.1±22.0 °C at 760 mmHg. |
| Q: What is the LogP of pyrazine-2-carboxylic acid? |
| A: LogP of pyrazine-2-carboxylic acid is -1.36. |
| Q: What are the upstream materials of pyrazine-2-carboxylic acid? |
| A: Related upstream materials(CAS) of pyrazine-2-carboxylic acid: 89-01-0;109-08-0;13925-00-3;98-96-4;13961-37-0;13481-25-9;6924-68-1;123-32-0;34569-20-5;107-21-1. |
| Q: What is the molecular weight of pyrazine-2-carboxylic acid? |
| A: Molecular weight of pyrazine-2-carboxylic acid is 124.10. |
| Q: What are the uses of pyrazine-2-carboxylic acid? |
| A: Main uses of pyrazine-2-carboxylic acid: Pyrazine-2-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| Q: What is the safety information for pyrazine-2-carboxylic acid? |
| A: Safety information for pyrazine-2-carboxylic acid: S22-S24/25. |
| Q: What is the English name of pyrazine-2-carboxylic acid? |
| A: The English name of pyrazine-2-carboxylic acid is pyrazine-2-carboxylic acid. |
| Q: What English synonyms does pyrazine-2-carboxylic acid have? |
| A: English synonyms of pyrazine-2-carboxylic acid: MFCD00006130, 2-Pyrazinecarboxylic acid, Pyrazinoic acid, Pyrazine-2-carboxylic acid, EINECS 202-718-1, Pyrazine Carboxylic Acid. |
| Q: What is the InChIKey of pyrazine-2-carboxylic acid? |
| A: InChIKey of pyrazine-2-carboxylic acid is NIPZZXUFJPQHNH-UHFFFAOYSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |