4-FLUORO-4'-BROMOCHALCONE

Modify Date: 2025-08-25 17:10:38

4-FLUORO-4'-BROMOCHALCONE structure	Common Name	4-FLUORO-4'-BROMOCHALCONE
	CAS Number	98991-32-3	Molecular Weight	305.14
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₀BrFO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4-FLUORO-4'-BROMOCHALCONE

CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research[1].

Name	1-(4-bromophenyl)-3-(4-fluorophenyl)prop-2-en-1-one
Synonym	More Synonyms

Description	CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	hMAO-B:0.031 μM (IC50) hMAO-B:0.010 μM (Ki)
References	[1]. Thomas Parambi DG, et al. Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study. Comput Biol Chem. 2023 Aug;105:107899.

Molecular Formula	C₁₅H₁₀BrFO
Molecular Weight	305.14
Exact Mass	303.99000
PSA	17.07000
LogP	4.48430

4-Fluorobenzaldehyde

CAS#:459-57-4

1-(4-Bromopheny...

CAS#:99-90-1

~98%

4-FLUORO-4'-BRO...

CAS#:98991-32-3

Literature: Tiwari, Urvashi; Ameta, Chetna; Rawal, Manish K.; Ameta, Rakshit; Punjabi, Pinki B. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 3 p. 432 - 439

4-Fluorobenzaldehyde

CAS#:459-57-4

1-(4-Bromopheny...

CAS#:99-90-1

CAS#:74497-02-2

~18%

4-FLUORO-4'-BRO...

CAS#:98991-32-3

Detail

Literature: El-Bayouki; Basyouni; El-Sayed; Tohamy; El-Henawy Croatica Chemica Acta, 2012 , vol. 85, # 3 p. 255 - 268

4-Fluorobenzaldehyde

CAS#:459-57-4

1-(4-Bromopheny...

CAS#:99-90-1

4-Fluoroaniline

CAS#:371-40-4

~18%

4-FLUORO-4'-BRO...

CAS#:98991-32-3

Detail

Literature: El-Bayouki; Basyouni; El-Sayed; Tohamy; El-Henawy Croatica Chemica Acta, 2012 , vol. 85, # 3 p. 255 - 268

Precursor 3
CAS#:459-57-4 4-Fluorobenzaldehyde CAS#:99-90-1 1-(4-Bromopheny... CAS#:371-40-4 4-Fluoroaniline
DownStream 0

2-Propen-1-one,1-(4-bromophenyl)-3-(4-fluorophenyl)

4-Fluoro-4'-bromochalcone

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-Fluoro-4'-bromochalcone
Price: Check
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DC Chemicals Limited
China
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-FLUORO-4'-BROMOCHALCONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
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Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: 4-FLUORO-4'-BROMOCHALCONE
Price: ￥Inquiry/1g ￥Inquiry/250mg ￥Inquiry/5g
Purity: 97.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

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Use of 4-FLUORO-4'-BROMOCHALCONE

Names

4-FLUORO-4'-BROMOCHALCONE Biological Activity

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Precursor & DownStream

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.