N-Demethyl Erythromycin A
N-Demethyl Erythromycin A structure
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Common Name | N-Demethyl Erythromycin A | ||
|---|---|---|---|---|
| CAS Number | 992-62-1 | Molecular Weight | 719.90 | |
| Density | 1.21g/cm3 | Boiling Point | 818.1ºC at 760mmHg | |
| Molecular Formula | C36H65NO13 | Melting Point | 142-144ºC | |
| MSDS | N/A | Flash Point | 448.6ºC | |
Use of N-Demethyl Erythromycin AN-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic[1]. |
Summary: N-Deacetylerythromycin A (N-Demethyl Erythromycin A), a compound with CAS number 992-62-1 and molecular formula C36H65NO13, has a molecular weight of 719.90. Its melting point is 142-144°C and density is 1.21g/cm³. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | N-Demethyl Erythromycin A |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | N-Demethylerythromycin A is a metabolite of Erythromycin A. Erythromycin A is an antibiotic[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.21g/cm3 |
|---|---|
| Boiling Point | 818.1ºC at 760mmHg |
| Melting Point | 142-144ºC |
| Molecular Formula | C36H65NO13 |
| Molecular Weight | 719.90 |
| Flash Point | 448.6ºC |
| Exact Mass | 719.44600 |
| PSA | 202.70000 |
| LogP | 1.83430 |
| Index of Refraction | 1.534 |
| InChIKey | TXOOBKBDBNRQCF-QNPWSHAKSA-N |
| SMILES | CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(NC)C2O)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O |
| Storage condition | -20°C |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~86%
N-Demethyl Eryt... CAS#:992-62-1 |
| Literature: THE KITASATO INSTITUTE Patent: EP1559719 A1, 2005 ; Location in patent: Page/Page column 17 ; |
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~%
N-Demethyl Eryt... CAS#:992-62-1 |
| Literature: Journal of the American Chemical Society, , vol. 77, p. 3104,3105 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
|---|---|
| DownStream 0 | |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Antibacterial activity against macrolide-susceptible Staphylococcus aureus ATCC 29213
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL2064952
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Name: Antibacterial activity against macrolide-resistant Staphylococcus aureus ATCC 33591 c...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL2064953
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| N-Demethyl-erythromycin |
| Erythromyon,3'-demethyl |
| 3'-N-demethylerythromycin A |
| de-N-methyl-erythromycin |
| N-Demethylerythromycin A |
| N-desmethyl erythromycin |
| 3'-Demethylerythromyon |
| Des-N-methylerythromycin |
| Clarithromycin Impurity R (10 mg) (N-desmethyl erythromycin A) |
| Demethylerythromycin |
| de(N-methyl)erythromycin A |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of N-Demethyl Erythromycin A? |
| A: InChIKey of N-Demethyl Erythromycin A is TXOOBKBDBNRQCF-QNPWSHAKSA-N. |
| Q: What is the melting point of N-Demethyl Erythromycin A? |
| A: Melting point of N-Demethyl Erythromycin A is 142-144ºC. |
| Q: What are the storage conditions for N-Demethyl Erythromycin A? |
| A: Storage conditions for N-Demethyl Erythromycin A: -20°C. |
| Q: What is the boiling point of N-Demethyl Erythromycin A? |
| A: Boiling point of N-Demethyl Erythromycin A is 818.1ºC at 760mmHg. |
| Q: What is the molecular formula of N-Demethyl Erythromycin A? |
| A: Molecular formula of N-Demethyl Erythromycin A is C36H65NO13. |
| Q: What is the CAS number of N-Demethyl Erythromycin A? |
| A: CAS number of N-Demethyl Erythromycin A is 992-62-1. |
| Q: What is the LogP of N-Demethyl Erythromycin A? |
| A: LogP of N-Demethyl Erythromycin A is 1.83430. |
| Q: What is the molecular weight of N-Demethyl Erythromycin A? |
| A: Molecular weight of N-Demethyl Erythromycin A is 719.90. |
| Q: What is the English name of N-Demethyl Erythromycin A? |
| A: The English name of N-Demethyl Erythromycin A is N-Demethyl Erythromycin A. |
| Q: What is the SMILES notation of N-Demethyl Erythromycin A? |
| A: SMILES notation of N-Demethyl Erythromycin A is CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(NC)C2O)C(C)(O)CC(C)C(=O)C(C)C(O)C1(C)O. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |