Antibacterial agent 116

Modify Date: 2024-01-06 12:06:43

Antibacterial agent 116 structure	Common Name	Antibacterial agent 116
	CAS Number	99330-28-6	Molecular Weight	730.12
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₁₅Cl₂I₂NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antibacterial agent 116

Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain[1].

Name	Antibacterial agent 116

Description	Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antibacterial agent 116 (compound 1) can photo-label A. baumannii PBP1b, targets to R367 and E372 binding site[1].
References	[1]. Chuang HC, et al. Photoaffinity labeling of benzophenone-containing salicylanilide compounds to give an insight into the mechanism in disrupting peptidoglycan formation. Bioorg Med Chem. 2022 Aug 1;67:116819.

Molecular Formula	C₂₆H₁₅Cl₂I₂NO₄
Molecular Weight	730.12

Antibacterial agent 116

Use of Antibacterial agent 116

Names

Antibacterial agent 116 Biological Activity

Chemical & Physical Properties