Copper??Catalyzed Direct Synthesis of 3??Arylindoles

S Murru, AA Gallo, RS Srivastava

Index: Murru, Siva; Gallo, August A.; Srivastava, Radhey S. European Journal of Organic Chemistry, 2011 , # 11 p. 2035 - 2038

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Citation Number: 8

Abstract

Abstract A direct method for the preparation of various 3-arylindoles from their corresponding nitrosoarenes has been developed. Various substituted nitrosoarenes and alkynes were employed to obtain substituted indoles by using a Cu II–Cu 0 catalytic system. This is a two-step method that involves annulation of the nitrosoarene and alkyne followed by deoxygenation to give 3-arylindoles.

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