Journal of Heterocyclic Chemistry

Isomeric maleic anhydride adducts of phthalazine and pyridazine and their partial stereochemistry

MB Hocking

Index: Hocking,M.B. Journal of Heterocyclic Chemistry, 1977 , vol. 14, p. 829 - 837

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Citation Number: 3

Abstract

Abstract The addition of maleic anhydride to phthalazine is confirmed to form a five- membered pyrrolidino ring fusion to phthalazine VI, rather than a pyridophthalazine II, by means of synthetic and degradative experiments, and proton and carbon-13 nmr. Two of probable three isomers obtained have been isolated and the stereochemistry partially established. Comparison of the data obtained for this adduct with the data obtained for the ...