Investigations on the Efficiency of Regioselective C??Deuteration of Endocyclic Enolates

…, N Weerasooriya, GS Coumbarides

Index: Eames, Jason; Weerasooriya, Neluka; Coumbarides, Gregory S. European Journal of Organic Chemistry, 2002 , # 1 p. 181 - 187

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Citation Number: 16

Abstract

Abstract Regioselective C-deuteration of a series of Endocyclic enolates (derived from cyclic aryl ketones) was efficiently achieved by quenching the corresponding “base-free” enolate in the presence of a suitable deuterium source. We discuss the structural nature of the deuterium donor and comment on the use of additives within this deuteration step.