The Journal of Organic Chemistry

Synthesis of highly functionalized flavones and chromones using cycloacylation reactions and C-3 functionalization. A total synthesis of hormothamnione

LW McGarry, MR Detty

Index: McGarry, Lynda W.; Detty, Michael R. Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4349 - 4356

Full Text: HTML

Citation Number: 78

Abstract

The cycloacylations of hydroxy. and methoxy-substituted phenols with aryl-and alkylpropiolic acids using Eaton's reagent (10% phosphorus pentoxide in methanesulfonic acid) gives highly substituted flavones and chromonea in up to 63% yield. Styrylchromones were prepared from 2-methylchromones by condensation reactions of the 2-methyl group with various substituted benzaldehydes in sodium ethoxide and ethanol in almost quantitative ...

Related Articles:

Synthesis and anticancer activities of 5, 6, 7-trimethylbaicalein derivatives

[Liao, Hua-Lin; Hu, Ming-Kuan Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 10 p. 1162 - 1165]

Synthesis of Ring A??Modified Baicalein Derivatives

[Wang, Jun-Fei; Ding, Ning; Zhang, Wei; Wang, Peng; Li, Ying-Xia Helvetica Chimica Acta, 2011 , vol. 94, # 12 p. 2221 - 2230]

Novel synthesis of flavonoids of Scutellaria baicalensis Georgi.

[Chemical and pharmaceutical bulletin, , vol. 51, # 3 p. 339 - 340]

Obtaining new flavanones exhibiting antifungal activities by methyltrioxorhenium-catalyzed epoxidation–methanolysis of flavones

[Tetrahedron, , vol. 64, # 32 p. 7561 - 7566]

Novel synthesis of flavonoids of Scutellaria baicalensis Georgi.

[Chemical and pharmaceutical bulletin, , vol. 51, # 3 p. 339 - 340]

More Articles...