Tetrahedron Letters

Synthesis of Elasnin

JR Pfister

Index: Pfister, Juerg R. Tetrahedron Letters, 1980 , vol. 21, p. 1281 - 1284

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Citation Number: 10

Abstract

Elasnin (1) is an elastase inhibitor which has been isolated from culture broths of a strain of Streptomyces noboritoensis.* Its unique structure, formally related to that of the polyketide tetraacetic lactone, 3 has recently been elucidated. 4 We report here an effective synthesis