Arylation of diethyl 2-chloroazulene-1, 3-dicarboxylate with Grignard reagent

AH Chen, SC Chiu, YC Kuo

Index: Chen, Arh-Hwang; Chiu, Shu-Ching; Kuo, Yu-Chen Synthetic Communications, 2003 , vol. 33, # 15 p. 2701 - 2707

Full Text: HTML

Citation Number: 4

Abstract

Abstract Reaction of diethyl 2-chloroazulene-1, 3-dicarboxylate (2) with phenyl magnesium bromide, followed by oxidation with o-chloranil, gave diethyl 2-chloro-4-phenylazulene-1, 3- dicarboxylate (3), diethyl 2-chloro-5-phenylazulene-1, 3-dicarboxylate (4) and diethyl 6- phenylazulene-1, 3-dicarboxylate (5).