Complete relative stereochemistry of maitotoxin

W Zheng, JA DeMattei, JP Wu, JJW Duan…

Index: Zheng; DeMattei; Wu; Duan; Cook; Oinuma; Kishi Journal of the American Chemical Society, 1996 , vol. 118, # 34 p. 7946 - 7968

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Citation Number: 145

Abstract

By addressing the relative stereochemistry of the four acyclic portions via organic synthesis, the complete relative stereochemistry of maitotoxin (MTX) has been established as 1B. The relative stereochemistry of the C. 1-C. 15 portion was elucidated via a two-phase approach:(1) the synthesis of the eight diastereomers possible for model C, representing the C. 1-C. 11 portion, and the eight diastereomers possible for model D, representing the C. ...