Synlett

l-Proline-catalyzed asymmetric Michael addition of 2-oxindoles to enones: a convenient access to oxindoles with a quaternary stereocenter

MH Freund, SB Tsogoeva

Index: Synlett, , # 4 p. 503 - 507

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Citation Number: 17

Abstract

... Synlett 2011(4): 503-507 DOI: 10.1055 ... A new organocatalytic approach for 1,4-conjugate addition of 2-oxindoles to α,β-unsaturated ketones using the combination of readily available and nonexpensive l-proline and achiral trans-2,5-dimethylpiperazine as catalytic system ...

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