Synthesis of 2-substituted benzimidazoles catalyzed by FeCl3/Al2O3 under ultrasonic irradiation

GF Chen, XY Dong, FZ Meng, BH Chen…

Index: Chen, Guo-Feng; Dong, Xiao-Yun; Meng, Fan-Zhu; Chen, Bao-Hua; Li, Ji-Tai; Wang, Shu-Xiang; Bai, Guo-Yi Letters in Organic Chemistry, 2011 , vol. 8, # 7 p. 464 - 469

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Citation Number: 13

Abstract

Keywords: Aromatic aldehydes, benzimidazoles, FeCl3/Al2O3, o-phenylenediamine, ultrasonic. ... INTRODUCTION Benzimidazole derivatives have received much interest in the field of medicinal chemistry [1]. They exhibit significant activity against several viruses such as HIV [2], herpes (HSV-1) [3] and RNA influenza [4-5]. Because of their im- portance, the synthesis of substituted benzimidazoles has become a focus of synthetic organic chemistry. A ...

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