Tetrahedron letters

BF 3· Et 2 O promoted one-pot expeditious and convenient synthesis of 2-substituted benzimidazoles and 3, 1, 5-benzoxadiazepines

VK Tandon, M Kumar

Index: Tandon, Vishnu K.; Kumar, Manoj Tetrahedron Letters, 2004 , vol. 45, # 21 p. 4185 - 4187

Full Text: HTML

Citation Number: 74

Abstract

2-Substituted benzimidazoles and 3, 1, 5-benzoxadiazepines have been synthesized in excellent yields in a single pot by cyclodehydration of N-acyl-1, 2-phenylenediamines and N, N′-diacyl-1, 2-phenylenediamines prepared in situ from the corresponding 1, 2- phenylenediamines and an acid chloride, respectively.

Related Articles:

Synthesis of 2-substituted benzimidazoles catalyzed by FeCl3/Al2O3 under ultrasonic irradiation

[Chen, Guo-Feng; Dong, Xiao-Yun; Meng, Fan-Zhu; Chen, Bao-Hua; Li, Ji-Tai; Wang, Shu-Xiang; Bai, Guo-Yi Letters in Organic Chemistry, 2011 , vol. 8, # 7 p. 464 - 469]

Rh (I)-catalyzed arylation of heterocycles via CH bond activation: expanded scope through mechanistic insight

[Lewis, Jared C.; Berman, Ashley M.; Bergman, Robert G.; Ellman, Jonathan A. Journal of the American Chemical Society, 2008 , vol. 130, # 8 p. 2493 - 2500]

Palladium-catalyzed N-heteroannulation of N-allyl-or N-benzyl-2-nitrobenzenamines: synthesis of 2-substituted benzimidazoles

[Hubbard, Jeremiah W.; Piegols, Adam M.; Soederberg, Bjoern C.G. Tetrahedron, 2007 , vol. 63, # 30 p. 7077 - 7085]

Synthesis of benzimidazoles by Cu 2 O-catalyzed cascade reactions between o-haloaniline and amidine hydrochlorides

[Qu, Yanyang; Pan, Lei; Wu, Zhiqing; Zhou, Xiangge Tetrahedron, 2013 , vol. 69, # 6 p. 1717 - 1719]

One??pot synthesis of benzimidazoles from o??nitroanilines under microwaves via a reductive cyclization

[Surpur, Mandar P.; Singh, Pankajkumar R.; Patil, Sachin B.; Samant, Shriniwas D. Synthetic Communications, 2007 , vol. 37, # 8 p. 1375 - 1379]

More Articles...