Stereochemical course of an enzyme-catalyzed allene-acetylene isomerization

JM Schwab, DCT Lin

Index: Schwab, John M.; Lin, Daniel C. T. Journal of the American Chemical Society, 1985 , vol. 107, # 21 p. 6046 - 6052

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Citation Number: 23

Abstract

Abstract: An allene-acetylene isomerase (AAI) isolated from hog liver interconverts the N- acetylcysteamine thio ester of 3-decynoic acid (3-decynoyl-NAC) and (+)-2, 3-decadienoyl- NAC. It is thus far the only enzyme that has been isolated that produces (or utilizes) an allenic compound and that is not inactivated by that same allene. Although physical and kinetic characteristics of the enzyme have previously been obtained, details of its ...