General method of diastereo-and enantioselective synthesis of β-hydroxy-α-amino acids by condensation of aldehydes and ketones with glycine

YN Belokon, AG Bulychev, SV Vitt…

Index: Journal of the American Chemical Society, , vol. 107, # 14 p. 4252 - 4259

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Citation Number: 173

Abstract

... 0002-7863/85/1507-4252$01,50/0 0 1985 American Chemical Society Page 2. ... An important advantage of this reaction is its high diastereo- and enantioselectivity which permit us to obtain almost pure (R)-threo-3 with an ee greater than 80%. ... J. Am. Chem. Soc., Vol, 107, No. ...

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