Journal of medicinal chemistry

Solvolysis of 19-hydroxy steroid derivatives

WG Dauben, DA Ben-Efraim

Index: Dauben,W.G.; Ben-Efraim,D.A. Journal of Medicinal Chemistry, 1968 , vol. 11, p. 287 - 291

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Citation Number: 7

Abstract

Chim. Acta, 47, 1961 (1964). iiidepeiideiit of the reaction conditions; however, it was found that only in neutral solution could pure IITa be obtuiiied by direct recrystallization of the reactiori mixture. Chromatography of the mother liquori yielded 28% of n mixture of isomer V (iii equilibrium with heniiketal 1-ketal TIb. The structure of VIb its spectral properties, it-coiiver arid> olutioii, and it< 1) reparatioii oil heatiiig 1-under refiuu\ nth p-tciluenesulfoiiic: wid iii ...