Monophenolic 2-amino-1-indanone and 2-amino-1-tetralone derivatives: synthesis and assessment of dopaminergic activity

…, V Cuomo, G Racagni, E Juliano, AC Rovescalli

Index: Perrone; Berardi; Bettoni; Tortorella; Cuomo; Racagni; Juliano; Rovescalli European Journal of Medicinal Chemistry, 1987 , vol. 22, # 5 p. 417 - 419

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Citation Number: 3

Abstract

Abstract Monophenolic 2-amino-1-indanones and 2-amino-1-tetralones having various substituents on the nitrogen atom were prepared and their activities in vitro on D 1 and D 2 dopaminergic receptors were assayed. All compounds were inactive in binding assays and this inactivity is discussed.