Journal of the American Chemical Society

ALKYL-ALLYL-BARBITURIC ACIDS1

EH Volwiler

Index: Volwiler Journal of the American Chemical Society, 1925 , vol. 47, p. 2239

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Citation Number: 15

Abstract

Of the numerous types of compounds that have been found to have hypnotic action, none has attained such extensive use as the derivatives of barbituric acid, or malonyl urea. This is due to the relatively greater ease of preparation, higher efficiency and lower toxicity of these compounds. These barbituric acid derivatives, in which the substituent groups are both attached to the 5 carbon atom, were introduced into therapeutic use by Fischer and von ...