Chemical Communications

Copper (ii)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives

Y Zhu, C Zhai, L Yang, W Hu

Index: Zhu, Yingguang; Zhai, Changwei; Yang, Liping; Hu, Wenhao Chemical Communications, 2010 , vol. 46, # 16 p. 2865 - 2867

Full Text: HTML

Citation Number: 22

Abstract

Copper (II) complexes are efficient catalysts in three-component reactions of aryl diazoacetates with alcohols and chalcones to give γ-hydroxyketone derivatives in high yield with excellent diastereoselectivity. The resulting coupling adducts can be easily converted into furan-containing oligoaryls, tetrahydrofuran and 2, 3-dihydrofuran derivatives.

Related Articles:

Brønsted Acid-Catalyzed Cycloisomerization of But-2-yne-1, 4-diols with or without 1, 3-Dicarbonyl Compounds to Tri-and Tetrasubstituted Furans

[Mothe, Srinivasa Reddy; Lauw, Sherman Jun Liang; Kothandaraman, Prasath; Chan, Philip Wai Hong Journal of Organic Chemistry, 2012 , vol. 77, # 16 p. 6937 - 6947]

An efficient furan synthesis using heterogeneous catalysis

[Hayes, Simon J.; Knight, David W.; Menzies, Melanie D.; O'Halloran, Mark; Tan, Wen-Fei Tetrahedron Letters, 2007 , vol. 48, # 43 p. 7709 - 7712]

Synthesis of Polysubstituted Furans via Copper-Mediated Annulation of Alkyl Ketones with α, β-Unsaturated Carboxylic Acids

[Yang, Yuzhu; Yao, Jinzhong; Zhang, Yuhong Organic Letters, 2013 , vol. 15, # 13 p. 3206 - 3209]

Thiazolium-catalyzed additions of acylsilanes: a general strategy for acyl anion addition reactions

[Mattson, Anita E.; Bharadwaj, Ashwin R.; Zuhl, Andrea M.; Scheidt, Karl A. Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5715 - 5724]

Thiazolium-catalyzed additions of acylsilanes: a general strategy for acyl anion addition reactions

[Mattson, Anita E.; Bharadwaj, Ashwin R.; Zuhl, Andrea M.; Scheidt, Karl A. Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5715 - 5724]

More Articles...