Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2, 4-diamino-7-aminoalkoxy-quinazolines.

F Liu, X Chen, A Allali-Hassani, AM Quinn…

Index: Journal of Medicinal Chemistry, , vol. 53, # 15 p. 5844 - 5857

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Citation Number: 111

Abstract

... Journal of Medicinal ... Center for Integrative Chemical Biology and Drug Discovery, Division of Medicinal Chemistry and Natural ... pluripotent stem (iPS) cells.(23, 24) Thus, small molecule PKMT inhibitors could play an important role in stem cell biology and regenerative medicine. ...