The Journal of Organic Chemistry

A simple and convenient method for esterification of tryptophan and other amino acids

I Arai, I Muramatsu

Index: Arai, Isamu; Muramatsu, Ichiro Journal of Organic Chemistry, 1983 , vol. 48, # 1 p. 121 - 123

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Citation Number: 29

Abstract

'Measured in 1-2% amino acids, such as tryptophan, are hardly esterified in a strongly acidic medium and at high temperature. In 1963, Wilchek et al. e synthesized tryptophan benzyl ester via N-carboxy anhydride with phosgene, followed by treatment of the intermediate with benzyl alcohol. Recently, Williams et al. 1 reported the preparation of tryptophan benzyl ester by the thermal decomposition of a benzyldimethylanilinium salt of N-protected ...

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