Chemoselective hydrolysis of amides in the presence of esters by copper (II)/glyoxal: metal complexation as the core motif for selective amide activation
L Singh, RN Ram
Index: Singh, Latika; Ram, Ram N. Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 710 - 711
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Citation Number: 14
Abstract
Summary: A general method for selective hydrolysis of amides in the presence of esters with Cu(II)/glyoxal in aqueous medium is reported. The hydrolyses of carboxamides and carboxylic esters are classical reactions of fundamental importance in chemistry and biology. Due to the
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