Synthesis and antinociceptive activity of 9-phenyl-oxy or 9-acyl-oxy derivatives of xanthene, thioxanthene and acridine

EF Llama, C del Campo, M Capo, M Anadon

Index: Llama, Emilio F.; Campo, Carmen del; Capo, Miguel; Anadon, Maria European Journal of Medicinal Chemistry, 1989 , vol. 24, p. 391 - 396

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Citation Number: 32

Abstract

The synthesis of 9-alkyl-oxy or 9-acyl-oxy derivatives of xanthene, thioxanthene and acridine is reported. A potent antinociceptive activity was confirmed for the 9-phenyl-9-propionyl-oxy derivative bearing an oxygen or sulfur atom in the heteroaromatic structure. ... Synthèse de dérivés phényl-9-alkoxy-9 ou acyl-oxy-9 du xanthène, thioxanthène et de l'acridine. Une forte activité antinociceptive se manifeste lorsque le dérivé phényl-9-propionyl-oxy-9, porte un ...

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