9-Phenyl-9H-xanthen-9-ol

Modify Date: 2025-08-25 23:25:50

9-Phenyl-9H-xanthen-9-ol Structure
9-Phenyl-9H-xanthen-9-ol structure
Common Name 9-Phenyl-9H-xanthen-9-ol
CAS Number 596-38-3 Molecular Weight 274.313
Density 1.3±0.1 g/cm3 Boiling Point 432.6±24.0 °C at 760 mmHg
Molecular Formula C19H14O2 Melting Point 158-161 °C(lit.)
MSDS N/A Flash Point 199.7±17.1 °C

 Use of 9-Phenyl-9H-xanthen-9-ol


Antioxidant agent-15 (Compound 4) is a potent antioxidant inhibition activity, with the IC50 of 15.44 nM. Antioxidant agent-15 inhibits tumor cell growth in Hela, Hep G2 and Caco-2 cells, with the IC50 of 395.26, 400.4 and 24.6 nM, respectively[1].

 Names

Name 9-Phenylxanthen-9-ol
Synonym More Synonyms

 9-Phenyl-9H-xanthen-9-ol Biological Activity

Description Antioxidant agent-15 (Compound 4) is a potent antioxidant inhibition activity, with the IC50 of 15.44 nM. Antioxidant agent-15 inhibits tumor cell growth in Hela, Hep G2 and Caco-2 cells, with the IC50 of 395.26, 400.4 and 24.6 nM, respectively[1].
Related Catalog
Target

95.26, 400.4 and 24.6 nM (Hela、Hep G2 and Caco-2 cells)[1]

References

[1]. Abualhasan M, et al. Biological Evaluation of Xanthene and Thioxanthene Derivatives as Antioxidant, Anticancer, and COX Inhibitors. ACS Omega. 2023;8(41):38597-38606.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 432.6±24.0 °C at 760 mmHg
Melting Point 158-161 °C(lit.)
Molecular Formula C19H14O2
Molecular Weight 274.313
Flash Point 199.7±17.1 °C
Exact Mass 274.099365
PSA 29.46000
LogP 3.60
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.674
InChIKey CVZUPKFPOSRRSK-UHFFFAOYSA-N
SMILES OC1(c2ccccc2)c2ccccc2Oc2ccccc21

 Safety Information

Safety Phrases S22-S24/25
WGK Germany 3
HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 9-Phenyl-9H-xanthen-9-olBioassay

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Name: Binding affinity to DNA assessed as DNA intercalation at 250 uM
Source: ChEMBL
Target: Nucleic Acid
External Id: CHEMBL1070309
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: Binding affinity to DNA assessed as DNA intercalation at 50 uM
Source: ChEMBL
Target: Nucleic Acid
External Id: CHEMBL1070308
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
Name: Cytotoxicity against human HeLa cells after 48 hrs
Source: ChEMBL
Target: HeLa
External Id: CHEMBL1070305
Name: Cytotoxicity against human MCF7 cells after 48 hrs
Source: ChEMBL
Target: MCF7
External Id: CHEMBL1070304
Name: Cytotoxicity against human DU145 cells after 48 hrs
Source: ChEMBL
Target: DU-145
External Id: CHEMBL1070303
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 Synonyms

9-phenylxanthen-9-ol
EINECS 209-882-3
9-Phenyl-9H-xanthen-9-ol
MFCD00005058
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