Tetrahedron Letters

Selective aerobic oxidation of allylic and benzylic alcohols catalyzed by N-hydroxyindole and copper (I) chloride

…, V Kartika, YS Tan, RD Webster, K Narasaka

Index: Shen, Shu-Su; Kartika, Vita; Tan, Ying Shan; Webster, Richard D.; Narasaka, Koichi Tetrahedron Letters, 2012 , vol. 53, # 8 p. 986 - 990

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Citation Number: 20

Abstract

In the presence of copper (I) chloride, tert-butyl 1-hydroxy-2-methyl-6-trifluoromethyl-1H- indole-3-carboxylate acted as a catalyst for the chemoselective aerobic oxidation of allylic and benzylic alcohols. A variety of primary and secondary allylic and benzylic alcohols were oxidized into the corresponding α, β-unsaturated carbonyl compounds in good yields without affecting non-allylic alcohols.

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