Synthesis and selected transformations of 3-oxido-1H-imidazole-4-carboxamides
G Mloston, M Jasiński
Index: Mloston, Grzegorz; Jasinski, Marcin Collection of Czechoslovak Chemical Communications, 2010 , vol. 75, # 8 p. 871 - 885
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Citation Number: 12
Abstract
Abstract An efficient synthesis of new N-alkyl-and N-aryl-3-oxido-1H-imidazole-4- carboxamides based on exploration of inexpensive, commercially available ethyl acetoacetate, paraformaldehyde and primary amines is described. Representative compounds were tested in selected transformations, such as 'sulfur-transfer reaction'leading to imidazole-2-thiones and isomerization to corresponding imidazol-2-ones. Strong ...
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